Holcombe E Grier Selected Research

Ifosfamide

10/2016	Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.
1/2016	Intensified Chemotherapy With Dexrazoxane Cardioprotection in Newly Diagnosed Nonmetastatic Osteosarcoma: A Report From the Children's Oncology Group.
1/2015	Age, Tumor Characteristics, and Treatment Regimen as Event Predictors in Ewing: A Children's Oncology Group Report.
11/2012	Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group.
7/2010	Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects.
5/2009	Chemotherapy: The role of ifosfamide and etoposide in Ewing sarcoma.
2/2008	Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group.
12/2007	Treatment of metastatic Ewing sarcoma/primitive neuroectodermal tumor of bone: evaluation of increasing the dose intensity of chemotherapy--a report from the Children's Oncology Group.
8/2006	Local control in pelvic Ewing sarcoma: analysis from INT-0091--a report from the Children's Oncology Group.
6/2005	Phase II trial of neoadjuvant vincristine, ifosfamide, and doxorubicin with granulocyte colony-stimulating factor support in children and adolescents with advanced-stage nonrhabdomyosarcomatous soft tissue sarcomas: a Pediatric Oncology Group Study.

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Holcombe E Grier Research Topics

Disease

25	Neoplasms (Cancer) 01/2019 - 12/2002
15	Ewing Sarcoma (Sarcoma, Ewing) 12/2021 - 02/2003
11	Osteosarcoma (Osteogenic Sarcoma) 01/2019 - 01/2002
6	Neoplasm Metastasis (Metastasis) 12/2019 - 04/2006
6	Primitive Neuroectodermal Tumors (PNET) 12/2007 - 02/2003
4	Sarcoma (Soft Tissue Sarcoma) 01/2019 - 02/2003
3	Cardiotoxicity 01/2019 - 08/2011
3	Left Ventricular Dysfunction 01/2019 - 01/2016
2	Rhabdomyosarcoma 01/2018 - 03/2004
2	Infections 10/2016 - 01/2002
2	Aggressive Fibromatosis (Desmoid) 07/2013 - 02/2007
2	Disease Progression 07/2013 - 04/2003
2	Thrombocytopenia (Thrombopenia) 08/2011 - 03/2009
2	Neutropenia 08/2011 - 03/2009
1	Heart Failure 01/2019
1	Infarction (Infarctions) 10/2016
1	Necrosis 01/2016
1	Ovarian Cysts (Ovarian Cyst) 07/2013
1	Fatigue 08/2011
1	Chronic Disease (Chronic Diseases) 06/2009
1	Hearing Loss (Hearing Impairment) 03/2009
1	Second Primary Neoplasms (Neoplasms, Second) 12/2007
1	Vomiting 02/2007
1	Nausea 02/2007
1	Fibroma (Fibromatosis) 02/2007
1	Anemia 02/2007
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2007
1	Long Term Adverse Effects 04/2006
1	Neuroblastoma 12/2003
1	Margins of Excision 10/2003
1	Fibrosarcoma 12/2002

Drug/Important Bio-Agent (IBA)

12	Ifosfamide FDA LinkGeneric 10/2016 - 01/2002
9	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 06/2005
9	Etoposide (VP 16)FDA LinkGeneric 10/2016 - 01/2002
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2021 - 08/2006
5	Methotrexate (Mexate)FDA LinkGeneric 10/2016 - 02/2007
5	Cisplatin (Platino)FDA LinkGeneric 10/2016 - 02/2008
4	Vincristine (Oncovin)FDA LinkGeneric 12/2021 - 06/2005
3	AnthracyclinesIBA 01/2019 - 08/2011
2	Pharmaceutical PreparationsIBA 12/2021 - 02/2008
2	Topotecan (Hycamtin)FDA LinkGeneric 12/2021 - 01/2006
2	Dexrazoxane (Zinecard)FDA LinkGeneric 01/2019 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 03/2009
2	Transaminases (Aminotransferases)IBA 08/2011 - 02/2007
1	Melphalan (Alkeran)FDA LinkGeneric 12/2019
1	Busulfan (Busulfex)FDA Link 12/2019
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019
1	pro-brain natriuretic peptide (1-76)IBA 01/2019
1	Sirolimus (Rapamycin)FDA Link 01/2018
1	Forkhead Box Protein O1IBA 01/2018
1	Insulin (Novolin)FDA Link 01/2016
1	Biological ProductsIBA 01/2016
1	microbial alkaline proteinase inhibitor (MAPI)IBA 01/2016
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2016
1	Tamoxifen FDA LinkGeneric 07/2013
1	Sulindac (Copal)FDA LinkGeneric 07/2013
1	Sunitinib (Sutent)FDA Link 08/2011
1	Cytarabine (Cytosar-U)FDA LinkGeneric 03/2009
1	Progesterone Receptors (Progesterone Receptor)IBA 09/2008
1	Estrogens (Estrogen)FDA Link 09/2008
1	ParaffinIBA 05/2007
1	Monoclonal AntibodiesIBA 05/2007
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 05/2007
1	Vinblastine (Vinblastine Sulfate)FDA Link 02/2007
1	Dactinomycin (Actinomycin)FDA LinkGeneric 08/2006
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2006
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 06/2005
1	Drug CombinationsIBA 02/2003

Therapy/Procedure

20	Drug Therapy (Chemotherapy) 12/2021 - 01/2002
13	Therapeutics 10/2016 - 01/2002
5	Radiotherapy 11/2012 - 10/2003
3	Neoadjuvant Therapy 01/2018 - 10/2003
3	Induction Chemotherapy 01/2016 - 01/2002
2	Terminal Care (Care, Terminal) 04/2008 - 12/2005
1	Palliative Care (Palliative Therapy) 04/2008
1	Neck Dissection (Radical Neck Dissection) 04/2006
1	Adjuvant Chemotherapy 04/2003